Brian Hanley
7 min readJan 7, 2018

Many transgender and gay people are dual sex chimeras

So what’s a chimera? It’s the opposite of twins in one way. It’s also when you are your own twin. Instead of your brother or sister being born with you, the two of you smoosh together, and you’re born as one child. In other words, sometimes two embryos merge one.

We know this happens.We don’t know exactly how often it happens, but it happens. Most people don’t get tested to find out if they are a chimera. Boklage set the upper limit for this kind of chimerism at 60%. But it’s probably 10%-15% of the population.

Possible combinations of embryos.

Do the math on it, and about half the time, there should be a brother-sister pair of twins that merge into one person. So probably 5% to 8% or so of all births should be mixed-sex people. That’s a lot.

You can see how ectoderm and endoderm would generally be formed by different blastocycsts after a collision and sticking together.

What happens when two separate embryonic blastocysts merge into one? Based on what we think we know, most of the time, one of those wraps around the other, and becomes the ectoderm (outer layer) and the other becomes the endoderm (inner core). There’s also a mesoderm layer. What happens with that is anybody’s guess. So, here’s the really interesting part. Gonads (testicles and ovaries), internal organs like liver, intestines, and the heart are made from endoderm.

Brain

Guess what is made from ectoderm? The brain and nervous system. The brain starts as a fold in the ectoderm. Skin should also be made from ectoderm.

Now, the obvious question from here is whether it stays that way, or should the brains and gonads of mixed-sex people be a patchwork of cells from both? Except in very rare cases, no, individual organs will be from one twin or the other. There will be a little infiltration. But, in the brain, we have more than just nerves.

Astrocytes in a brain

The brain also has glial cells (astrocytes, oligodendrocytes, and microglia), and these outnumber neurons. Astrocytes may even be part of the brain’s communications network, or have their own, parallel net. Microglial cells have immune system functions. Whether all these cell types start from the the same ectoderm as the nerves do, I do not know. They might not. So we might have brains that have a mix of male and female, where the nerves are one sex and other cell types are the opposite sex.

How many people are born with a male brain in a female body? Based on the numbers above, it should be around 2.5% to 3.5%. And similar numbers for female brains in male bodies. Those numbers are pretty darn close to what surveys show for homosexuality.

Transgender identification is mostly new — although the mahou of the South Pacific is an example of ancient societal familiarity. Transgender has been morphing a great deal since I published my paper — so much so it is almost unrecognizable. I think that there are people who genuinely experience life as “I’m the wrong sex.” We know that identical twins where one had a surgical accident in infancy, and was surgically altered, and then raised as a girl with hormones, most know they should be boys. I think that transgender in 2024 includes a lot of people (mostly young females) who are confused or having stress over puberty. To those, I must add those who are taking advantage of a new opportunity to game the system to obtain sports scholarships by competing unfairly against females. Sex based differences are present before puberty. Add to this, a contingent that want to act out autogynephilia. And there is a growing contingent who use new laws to game the legal system, as a cover for pedophilia, or simply be highly effective rapist predators, especially inside of women’s prison. The reports are too numerous to discount at this point.

I don’t think that every gay person is a chimera. But I think that the majority are likely to be. And I think that a core group of trans identifying people are genuine, and may have female brains. Those should be diagnosable by testing for dual sex chimerism. Most such people should find a way too adjust to their homosexuality.

These days (2024) I have been asked my opinion on the wave of law and medical intervention to trans-sex children. I have to say that I think it is quite criminal, a RICO case probably. First, children and their parents are being sold a lie — that their child can change sex. This is impossible. The procedure claiming to do it does nothing of the sort. It is sterilization, both chemical and surgical plus surgeries that are carried out by unqualified surgeons without any agreed upon standards. The scarring I have seen from such surgeries is unacceptable butchery not conforming to plastic surgery standards. Second, the idea that a child could conceivably give informed consent is outrageous. Medical ethics is an area I have published in. No child can consent to it.

Third, there is absolutely no excuse for pushing transgender “medicine” on children. None. The science is against it, and no legitimate science ever justified it. The “Dutch protocol” that is being implemented across the USA and Europe, never showed it helped the kids, and to publish, the authors removed a child who died from the intervention — this latter is reprehensible academic and ethical misconduct. Science says that “rapid onset” gender dysphoria is real — translated into normal speech, those kids are confused, bowing to peer pressure mostly. Serious concerns have been voiced by psychiatry — many have other psychiatric problems they want to escape. A growing contingent of young are de-transitioners, often with steps that cannot be undone. If there are de-transitioners, that should mean—stop all interventions immediately. If it was a clinical trial, it would be shut down. This paper from Sweden is the first long-term followup ever done on “sex reassignment” found a suicide rate roughly 20 times that of the controls.

My view is that “sex reassignment” medical interventions of any kind should be illegal until the person is 26 years of age and fully informed, because 25 is an accepted figure for when the brain is finally mature. It should not be legal to call these interventions “sex reassignment”.

This popular format article you are reading comes from a paper I published 6 years ago in 2011. I am writing it because someone asked me to write it. Like most things, this really started years before 2011. I had thought of this before 2000. In grad school I talked about writing the paper, or trying to study it further. But I was discouraged from doing so by everyone I talked to. There may be acceptance of such studies in the humanities department on most campuses. And, some campuses might be willing to consider it. But I was counseled strongly to leave it alone— it would be a “career killer” in biology. So I left it during grad school.

I kept expecting someone else would publish a similar paper because it seemed so obvious. But nobody did. So I guess I am the originator of this theory of transgender and homosexuality, although I doubt very much that no other biologist thought of it. I think many must have hit on it before me, but decided it wasn’t worth it. I think this kind of chimerism probably explains most of what we see.

I haven’t exactly been embraced by trans-queer (TQ) groups so far. I’ve had a number of transgender identifying people write to me. I inform them of what the facts are, and so far, none has “transitioned”. Within the academic TQ community there is a very strong aversion to the “biology is destiny” idea. The TQ community is dominated by a social-speak and transhumanist thought that is quite divorced from biology. Recent evidence implicates a billionaire family, the Pritzkers, funding the top-down campaign to medically intervene for “ trans-children”. There are also TQ folk who reject this chimerism idea because to them it feels like they are not their biology. We are biological.

I understand why biological determinism has been rejected when gay and trans folk are indistinguishable physically from anybody else sharing their gross physical biological gender. Only by using modern laboratory methods is determination that a person is a dual sex chimera possible. People that look biologically male or female, but act the opposite, seems to many people to be obvious evidence of weirdness. That generates bullying, mockery, hurtful jokes and more.

Around the world are laws and religious dictates that in some cases have capital punishment for gay and transgender folk. There is widespread harassment and even the nice people have programs to set make gay and transgender people straight.

I think, though, that if this understanding of how chimerism works can be accepted, that it should go a long way toward acceptance.

Brian Hanley

Peer publications in biosciences, economics, terrorism, & policy. PhD - honors from UC Davis, BSCS, entrepreneur. Works on gene therapies & new monetary models.